Adrenalin

William Boericke 1922

The symptom guiding to this is, Sensation rf thoracic constriction zvith anguish. This, with vertigo, nausea and vomiting, have been produced by the drug. Abdominal pain. Shock or heart failure during anesthesia, as it causes very prompt rise of blood pressure by its action on nerve endings in the vessel wall.

William Boericke 1922

Hypodermically, 1*5 m. [1 : 1,000 solution] diluted in water. Internally, 5-30 m. of 1 : 1,000 solution. Caution. — On account of its affinity for oxygen, the drug easily decomposes in watery and dilute acid solutions. The solution must be protected from air and light. It must not be too frequently repeated, owing to cardiac and arterial lesions. For homoeopathic use 2x to 6x attenuation.

William Boericke 1922

branes promptly induces transient ischaemia, seen in a blanching, persisting several hours from conjunctival instillation. Its action is very prompt, efficient, avanescent, owing to rapid oxidation and therefore practically harmless, unless too frequently repeated, when atheroma and heart lesions — myocardial — in animals have been reported. The main action of Adrenalin is stimulation of the sympathetic endings, notably the splanchnic area, causing cousiriction of the peripheral arterioles, with resulting rise in blood pressure. This is especially observed in stomach, intestines ; less in uterus,

William Boericke 1922

medullary vagus stimulation, and strengthening of heart heat, increased myocardial contractility, resembling Digitalis ; increased glandular activity, glycosuria ; depression of respiratory center; contraction of muscular tissue of eye^ uterus, vagina; relaxation of muscular tissue of stomach, intestines, bladder. Uses. — Its chief therapeutic use depends on its vaso^ constriction action; therefore a most powerful and prompt astringent and heumostatic : and invaluable in checking capillary haemorrhages from all parts, where local or direct application is feasible, nose, ear, mouth, throat, laiynx, stomach, rectum, uterus, bladder. Complete bloodlessness, ischaemia, may be induced with impunity. Locally, solutions [1: 10,000-1 : 1,000] sprayed or applied on cotton have been very efficient in bloodless operations about the eye, nose, throat, and larynv Congestions of the ethmoid and sphenoid sinuses, also hay fever, have been markedly alleviated by warm spray of Adrenalin chloride, 1 : 5,000. Here compare Hepar lx, which will start up secretions and so facilitate drainage. WerlhofT’s disease hypodermically, 1:1,000. Ex- ADRENALIN — AiSCULUS HIPPOCASTA NUM 17 ternally, it has been used in neuritis, neuralgia, reflex pains, gout, rheumatism, as an ointment, 1-2 m. of 10 per cent, solution, along the nerve trunk at point of skin nearest its origin. Therapeutically, Adrenalin has been suggested in acute congestion of lungs. Grave’s and Addison’s diseases, arterio-sclerosis, chronic aortitis, angina pectoris, hajnv)philia, chlorosis, etc. Dr. P. Jousset reports success in treating, homoeopathically, cases of angina and of aortitis, sub-acute and chronic, when Adrenalin has been prescribed per os and in infiiiitesima!

William Boericke 1922

nil In brain and lungs. Furthermore, is noticed, sloiving of

William Boericke 1922

Adrenalin or Epinephrin, the active principle of the suprarenal gland, is employed as a chemical messenger in the regulation of the activities of the bod> ; in fact, its presence is essential to the activity of the sympathetic nerve. Adrenalin action on any part is the same as stimulation of the sympathetic nerve endings thereto. Local application fl : 1,000 solution] to mucous mem- 16